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| Single-Season Saves Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Saves | IP | Year | Career Leaderboard |
| 1. | Derrick Tucker | 43 | 85.0 | 2009 | |
| 2. | Todd Shuster | 41 | 86.3 | 2009 | |
| Jeff Mullett | 41 | 83.7 | 2007 | ||
| 4. | William Darosa | 40 | 83.0 | 2008 | |
| Marquis Moir | 40 | 69.7 | 2007 | ||
| 6. | Marquis Moir | 37 | 72.0 | 2008 | |
| 7. | Nathan West | 35 | 65.7 | 2009 | |
| Marquis Moir | 35 | 65.7 | 2009 | ||
| Derrick Tucker | 35 | 68.7 | 2008 | ||
| Matthew Bradley | 35 | 59.7 | 2007 | ||
| 11. | Nathan West | 34 | 70.0 | 2008 | |
| Michinari Bokkai | 34 | 63.3 | 2008 | ||
| 13. | Michinari Bokkai | 31 | 71.3 | 2007 | |
| Emerson Eccles | 31 | 68.0 | 2007 | ||
| Derrick Tucker | 31 | 58.0 | 2007 | ||
| 16. | Todd Shuster | 30 | 57.0 | 2008 | |
| Todd Shuster | 30 | 64.0 | 2007 | ||
| 18. | Basil Alvarado | 29 | 68.0 | 2008 | |
| 19. | Nathan West | 28 | 73.7 | 2007 | |
| 20. | William Darosa | 27 | 83.0 | 2009 | |
| William Darosa | 27 | 81.7 | 2007 | ||
| 22. | Matthew Bradley | 26 | 48.0 | 2008 | |
| 23. | Albert Buchan | 25 | 66.0 | 2008 | |
| Eusebio Poulos | 25 | 52.3 | 2008 | ||
| Jeff Mullett | 25 | 49.0 | 2008 | ||
| 26. | Eusebio Poulos | 24 | 60.0 | 2009 | |
| Eusebio Poulos | 24 | 58.3 | 2007 | ||
| 28. | Alfonso Pinelo | 22 | 90.7 | 2009 | |
| 29. | Walter Montero | 19 | 71.0 | 2009 | |
| Michinari Bokkai | 19 | 69.7 | 2009 | ||
| 31. | Albert Buchan | 18 | 51.0 | 2009 | |
| 32. | Rafael Fermos | 17 | 66.0 | 2007 | |
| 33. | Rob Rodriguz | 15 | 83.0 | 2009 | |
| Roger Johnson | 15 | 111.3 | 2008 | ||
| Basil Alvarado | 15 | 68.7 | 2007 | ||
| 36. | Rafael Fermos | 14 | 52.0 | 2009 | |
| 37. | Walter Montero | 13 | 79.7 | 2007 | |
| 38. | Brian Kuffrey | 12 | 106.7 | 2009 | |
| Jeff Mullett | 12 | 59.7 | 2009 | ||
| 40. | Anthony Corker | 11 | 50.7 | 2009 | |
| Sylvester Scott | 11 | 65.7 | 2008 | ||
| Scott Fuller | 11 | 95.0 | 2007 | ||
| 43. | Basil Alvarado | 9 | 53.7 | 2009 | |
| Brian Kuffrey | 9 | 107.0 | 2008 | ||
| Anthony Cronk | 9 | 67.7 | 2008 | ||
| 46. | Richard Barbieri | 8 | 88.3 | 2009 | |
| Matthew Bradley | 8 | 31.0 | 2009 | ||
| Jesse Peterson | 8 | 98.3 | 2007 | ||
| 49. | Val Via | 7 | 76.3 | 2009 | |
| Howard Goodman | 7 | 25.0 | 2009 | ||
| John Barrett | 7 | 105.0 | 2008 | ||
| James Westcott | 7 | 61.7 | 2008 | ||
| Dario Ozuna | 7 | 45.0 | 2008 | ||
| Pete Daye | 7 | 78.0 | 2007 | ||
| 55. | Scott Fuller | 6 | 43.0 | 2008 | |
| 56. | Ramon Velazquez | 5 | 66.3 | 2009 | |
| Thomas Holmes | 5 | 60.7 | 2009 | ||
| Maurice Folse | 5 | 38.3 | 2009 | ||
| Larry Saunders | 5 | 15.7 | 2009 | ||
| Emory Byars | 5 | 73.0 | 2008 | ||
| Emerson Eccles | 5 | 71.7 | 2008 | ||
| Kenneth Grant | 5 | 23.7 | 2008 | ||
| Juan Monroy | 5 | 104.3 | 2007 | ||
| Dan Ayala | 5 | 89.7 | 2007 | ||
| Gregory Riles | 5 | 78.3 | 2007 | ||
| Lorenzo Muņoz | 5 | 75.7 | 2007 | ||
| 67. | Francisco Graziano | 4 | 95.7 | 2009 | |
| Scott Dickerman | 4 | 95.3 | 2009 | ||
| Anthony Cronk | 4 | 64.7 | 2009 | ||
| Anthony Mejorado | 4 | 33.7 | 2009 | ||
| Juan Leon | 4 | 87.3 | 2008 | ||
| Eddie Barker | 4 | 62.7 | 2008 | ||
| Carl Litz | 4 | 59.0 | 2008 | ||
| Candido Sachs | 4 | 45.3 | 2008 | ||
| Carl Litz | 4 | 87.3 | 2007 | ||
| 76. | Erik Wells | 3 | 100.7 | 2009 | |
| Lorenzo Muņoz | 3 | 71.7 | 2009 | ||
| Oscar Moreno | 3 | 60.3 | 2009 | ||
| Candido Sachs | 3 | 55.0 | 2009 | ||
| Matthew Lawton | 3 | 53.3 | 2009 | ||
| Emory Byars | 3 | 49.7 | 2009 | ||
| Kenneth Grant | 3 | 45.0 | 2009 | ||
| Raul Cosenza | 3 | 44.0 | 2009 | ||
| Daniel McQuaig | 3 | 44.0 | 2009 | ||
| Dario Ozuna | 3 | 41.7 | 2009 | ||
| Richard Nelson | 3 | 40.7 | 2009 | ||
| Clyde Ploof | 3 | 37.3 | 2009 | ||
| Samuel Bell | 3 | 121.0 | 2008 | ||
| Bill Harris | 3 | 86.7 | 2008 | ||
| Andre Molina | 3 | 66.3 | 2008 | ||
| Juan Jensen | 3 | 66.0 | 2008 | ||
| Brian Garst | 3 | 58.0 | 2008 | ||
| Lorenzo Muņoz | 3 | 51.7 | 2008 | ||
| Val Via | 3 | 49.0 | 2008 | ||
| Matthew Lawton | 3 | 43.7 | 2008 | ||
| Henry Ingles | 3 | 28.3 | 2008 | ||
| Juan Jensen | 3 | 100.7 | 2007 | ||
| William Willsey | 3 | 97.0 | 2007 | ||
| Don Tokugawa | 3 | 89.3 | 2007 | ||
| Sebastian Villas | 3 | 66.0 | 2007 |
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